Publications

Please also find a cross-linked version of this list at Google Scholar.


2024  |  2023  |  2022  |  2021  |  2020  |  2019  |  2018  |  2017  |  2016  |  2015  |  2014  |  2013  |  2012  |  2011  |  2010  |  2009  |  2008  |  2007  |  2006  |  2005  |  2004  |  2002  |  20012000


2024

p21 Prevents the Exhaustion of CD4+ T Cells Within the Antitumor Immune Response Against Colorectal Cancer

Oana-Maria Thoma, Elisabeth Naschberger, Markéta Kubánková, Imen Larafa, Viktoria Kramer, Bianca Menchicchi, Susanne Merkel, Nathalie Britzen-Laurent, André Jefremow, et al.

Gastroenterology 166(2) 284-297 (2024) | Journal | PDF


Brillouin microscopy

Irina Kabakova, Jitao Zhang, Yuchen Xiang, Silvia Caponi, Alberto Bilenca, Jochen Guck, Guiliano Scarcelli

Nature Reviews Methods primers 4 8 (2024) | Journal


AI-driven projection tomography with multicore fibre-optic cell rotation

Jiawei Sun, Bin Yang, Nektarios Koukourakis, Jochen Guck, Juergen W. Czarske

Nature Communications 15 147 (2024) | Journal | PDF



2023

Bile Is a Selective Elevator for Mucosal Mechanics and Transport

Simon Hanio, Stephanie Möllmert, Conrad Möckel, Susobhan Choudhury, Andreas I. Höpfel, Theresa Zorn, Sebastian Endres, Jonas Schlauersbach, Lena Scheller, et al.

Molecular Pharmaceutics 20 6151-6161 (2023) | Journal


Small leucine-rich proteoglycans inhibit CNS regeneration by modifying the structural and mechanical properties of the lesion environment

Julia Kolb, Vasiliki Tsata, Nora John, Kyoohyun Kim, Conrad Möckel, Gonzalo Rosso, Veronika Kurbel, Asha Parmar, Gargi Sharma, et al.

Nature Communications 14 6814 (2023) | Journal | PDF


Varying the Stiffness and Diffusivity of Rod-Shaped Microgels Independently through Their Molecular Building Blocks

Yonca Kittel, Luis P. B. Guerzoni, Carolina Itzin, Dirk Rommel, Matthias Mork, Céline Bastard, Bernhard Häßel, Abdolrahman Omidinia-Anarkoli, Silvia P. Centeno, et al.

Angewandte Chemie, International Edition in English 62 e202309779 (2023) | Journal | PDF


Human T cells loaded with superparamagnetic iron oxide nanoparticles retain antigen-specific TCR functionality

Felix Pfister, Jan Dörrie, Niels Schaft, Vera Buchele, Harald Unterweger, Lucas R. Carnell, Patrick Schreier, Rene Stein, Markéta Kubánková, et al.

Frontiers in Immunology 14 1223695 (2023) | Journal | PDF


Highly Nonlinear Dynamics of In Vivo Deep-Tissue Interaction with Femtosecond Laser Pulses at 1030 nm

Soyeon Jun, Andreas Herbst, Kilian Scheffter, Nora John, Julia Kolb, Daniel Wehner, Hanieh Fattahi

arXiv:2308.05453 (2023) | PDF


IL-3 receptor signalling suppresses chronic intestinal inflammation by controlling mechanobiology and tissue egress of regulatory T cells

Karen Anne-Marie Ullrich, Julia Derdau, Carsten Baltes, Alice Battistella, Gonzalo Rosso, Stefan Uderhardt, Lisa Lou Schulze, Li-Juan Liu, Mark Dedden, et al.

Gut 72 2081-2094 (2023) | Journal | PDF


De novo identification of universal cell mechanics gene signatures

Marta Urbanska, Yan Ge, Maria Winzi, Shada Abuhattum Hofemeier, Syed Shafat Ali, Maik Herbig, Martin Kräter, Nicole Toepfner, Joanna Durgan, et al.

eLife 12 RP87930 | Journal | PDF


Alcohol-sourced acetate impairs T cell function by promoting cortactin acetylation

Vugar Azizov, Michael Hübner, Michael Frech, Jörg Hofmann, Markéta Kubánková, Dennis Lapuente, Matthias Tenbusch, Jochen Guck, Georg Schett, et al.

iScience 26(7) 107230 (2023) | Journal | PDF


Identification of a Distinct Monocyte-Driven Signature in Systemic Sclerosis Using Biophysical Phenotyping of Circulating Immune Cells

Alexandru-Emil Matei, Markéta Kubánková, Liyan Xu, Andrea-Hermina Györfi, Evgenia Boxberger, Despina Soteriou, Maria Papava, Julia Prater, Xuezhi Hong, et al.

Arthritis & Rheumatology 75(5) 768-781 (2023) | Journal | PDF


Dynamics of cell rounding during detachment

Agata Nyga, Katarzyna Plak, Martin Kräter, Marta Urbanska, Kyoohyun Kim, Jochen Guck, Buzz Baum

iScience 26(5) 106696 (2023) | Journal | PDF


Rapid single-cell physical phenotyping of mechanically dissociated tissue biopsies

Despina Soteriou, Markéta Kubánková, Christine Schweitzer, Rocío López-Posadas, Rahmita Pradhan, Oana-Maria Thoma, Andrea-Hermina Györfi, Alexandru-Emil Matei, Maximilian Waldner, et al.

Nature Biomedical Engineering 7 1392-1403 (2023) | Journal | PDF


Impact of crowding on the diversity of expanding populations

Carl F. Schreck, Diana Fusco, Yuya Karita, Stephen Martis, Jona Kayser, Marie-Cécilia Duvernoy, Oskar Hallatschek

Proceedings of the National Academy of Sciences of the United States of America 120(11) e2208361120 (2023) | Journal | PDF


A new hyperelastic lookup table for RT-DC

Lukas Daniel Wittwer, Felix Reichel, Paul Mueller, Jochen Guck, Sebastian Aland

Soft Matter 19(11) 2064-2073 (2023) | Journal | PDF


Shear rheology of methyl cellulose based solutions for cell mechanical measurements at high shear rates

Beyza Büyükurganci, Santanu Kumar Basu, Markus Neuner, Jochen Guck, Andreas Wierschem, Felix Reichel

Soft Matter 19 1739-1748 (2023) | Journal | PDF


Embracing the diversity of model systems to deconstruct the basis of regeneration and tissue repair

Aldine Amiel, Stephanie Tsai, Daniel Wehner

Development 150(3) dev.201579 (2023) | Journal


Image-based cell sorting using focused travelling surface acoustic waves

Ahmad Ahsan Nawaz, Despina Soteriou, Catherine Xu, Ruchi Goswami, Maik Herbig, Jochen Guck, Salvatore Girardo

Lab on a Chip 23 372-387 (2023) | Journal | PDF


Epithelial RAC1-dependent cytoskeleton dynamics controls cell mechanics, cell shedding and barrier integrity in intestinal inflammation

Luz del Carmen Martínez-Sánchez, Phuong Anh Ngo, Rashmita Pradhan, Lukas-Sebastian Becker, David Boehringer, Despina Soteriou, Markéta Kubánková, Christine Schweitzer, Tatyana Koch, et al.

Gut 72(2) 275-294 (2023) | Journal | PDF



2022

Evolutionary rescue of resistant mutants is governed by a balance between radial expansion and selection in compact populations

Serhii Aif, Nico Appold, Lucas Kampman, Oskar Hallatschek, Jona Kayser

Nature Communications 13 7916 (2022) | Journal | PDF


Caveolin-1 dolines form a distinct and rapid caveolae-independent mechanoadaptation system

Fidel-Nicolás Lolo, Nikhil Walani, Eric Seemann, Dobryna Zalvidea, Dácil María Pavón, Gheorghe Cojoc, Moreno Zamai, Christine Varis de Lesegno, Fernando Martínez de Benito, et al.

Nature Cell Biology 25 120-133 (2022) | Journal | PDF


Viscoelastic properties of suspended cells measured with shear flow deformation cytometry

Richard Gerum, Elham Mirzahossein, Mar Eroles, Jennifer Elsterer, Astrid Mainka, Andreas Bauer, Selina Sonntag, Alexander Winterl, Johannes Bartl, et al.

eLife 11 e78823 (2022) | Journal | PDF


PNIPAAm microgels with defined network architecture as temperature sensors in optical stretchers

Nicolas Hauck, Timon Beck, Gheorghe Cojoc, Raimund Schlüßler, Saeed Ahmed, Ivan Raguzin, Martin Mayer, Jonas Schubert, Paul Müller, et al.

Materials Advances 3 6179-6190 (2022) | Journal | PDF


Quantitative phase imaging through an ultra-thin lensless fiber endoscope

Jiawei Sun, Jiachen Wu, Ruchi Goswami, Salvatore Girardo, Liangcai Cao, Jochen Guck, Nektarios Koukourakis, Jürgen W. Czarske

Light: Science & Applications 11 204 (2022) | Journal | PDF


Long COVID: Association of Functional Autoantibodies against G-Protein-Coupled Receptors with an Impaired Retinal Microcirculation

Charlotte Szewczykowski, Christian Mardin, Marianna Lucio, Gerd Wallukat, Jakob Hoffmanns, Thora Schröder, Franziska Raith, Lennart Rogge, Felix Heltmann, et al.

International Journal of Molecular Sciences 23(13) 7209 (2022) | Journal | PDF


In vivo assessment of mechanical properties during axolotl development and regeneration using confocal Brillouin microscopy

Camilo Riquelme-Guzmán, Timon Beck, Sandra Edwards-Jorquera, Raimund Schlüßler, Paul Müller, Jochen Guck, Stephanie Möllmert, Tatiana Sandoval-Guzmán

Open Biology 12(6) 220078 (2022) | Journal | PDF


Adipose cells and tissues soften with lipid accumulation while in diabetes adipose tissue stiffens

Shada Abuhattum, Petra Kotzbeck, Raimund Schlüßler, Alexandra Harger, Angela Ariza de Schellenberger, Kyoohyun Kim, Joan-Carles Escolano, Torsten Müller, Jürgen Braun, et al.

Scientific Reports 12 10325 (2022) | Journal | PDF


Amoeboid-like migration ensures correct horizontal cell layer formation in the developing vertebrate retina

Rana Amini, Archit Bhatnagar, Raimund Schlüßler, Stephanie Möllmert, Jochen Guck, Caren Norden

eLife 11 e76408 (2022) | Journal | PDF


Best practices for reporting throughput in biomedical research

Maik Herbig, Akihiro Isozaki, Dino Di Carlo, Jochen Guck, Nao Nitta, Robert Damoiseaux, Shogo Kamikawaji, Eigo Suyama, Hirofumi Shintaku, et al.

Nature Methods 19 633-634 (2022) | Journal | PDF


mRNA Subtype of Cancer-Associated Fibroblasts Significantly Affects Key Characteristics of Head and Neck Cancer Cells

Barbora Peltanová, Hana Holcová Polanská, Martina Raudenská, Jan Balvan, Jiri Navrátil, Tomás Vicar, Jaromir Gumulec, Barbora Cechová, Martin Kräter, et al.

Cancers / Molecular Diversity Preservation International (MDPI) 14(9) 2286 (2022) | Journal | PDF


Depressive disorders are associated with increased peripheral blood cell deformability: a cross-sectional case-control study (Mood-Morph)

Andreas Walther, Anne Mackens-Kiani, Julian Eder, Maik Herbig, Christoph Herold, Clemens Kirschbaum, Jochen Guck, Lucas Wittwer, Katja Beesdo-Baum, et al.

Translational Psychiatry 12 150 (2022) | Journal | PDF


Changes in Blood Cell Deformability in Chorea-Acanthocytosis and Effects of Treatment With Dasatinib or Lithium

Felix Reichel, Martin Kräter, Kevin Peikert, Hannes Glaß, Philipp Rosendahl, Maik Herbig, Alejandro Rivera Prieto, Alexander Kihm, Giel Bosman, et al.

Frontiers in Physiology 13 852946 (2022) | Journal | PDF


Unbiased retrieval of frequency-dependent mechanical properties from noisy time-dependent signals

Shada Abuhattum, Hui-Shun Kuan, Paul Mueller, Jochen Guck, Vasily Zaburdaev

Biophysical Reports 2(3) 100054 (2022) | Journal | PDF


An explicit model to extract viscoelastic properties of cells from AFM force-indentation curves

Shada Abuhattum Hofemeier, Dominic Mokbel, Paul Müller, Despina Soteriou, Jochen Guck, Sebastian Aland

iScience 25(4) 104016 (2022) | Journal | PDF


An exception to the rule? Regeneration of the injured spinal cord in the spiny mouse

Daniel Wehner, Catherina G. Becker

Developmental Cell 57(4) 415-416 (2022) | Journal


Quantitative imaging of Caenorhabditis elegans dauer larvae during cryptobiotic transition

Kyoohyun Kim, Vamshidhar Gade, Teymuras V. Kurzchalia, Jochen Guck

Biophysical Journal 121(7) 1219-1229 (2022) | Journal | PDF


Nonlinear microscopy using impulsive stimulated Brillouin scattering for high-speed elastography

Benedikt Krug, Nektarios Koukourakis, Jochen Guck, Jürgen Czarske

Optics Express 30(4) 4748-4758 (2022) | Journal | PDF


Label-free imaging flow cytometry for analysis and sorting of enzymatically dissociated tissues

Maik Herbig, Karen Tessmer, Martin Nötzel, Ahmad Ahsan Nawaz, Tiago Santos-Ferreira, Oliver Borsch, Sylvia J. Gasparini, Jochen Guck, Marius Ader

Scientific Reports 12 963 (2022) | Journal | PDF


Machine learning assisted real-time deformability cytometry of CD34+ cells allows to identify patients with myelodysplastic syndromes

Maik Herbig, Angela Jacobi, Manja Wobus, Heike Weidner, Anna Mies, Martin Kräter, Oliver Otto, Christian Thiede, Marie-Theresa Weickert, et al.

Scientific Reports 12 870 (2022) | Journal | PDF


Mechanical spinal cord transection in larval zebrafish and subsequent whole-mount histological processing

Nora John, Julia Kolb, Daniel Wehner

STAR Protocols 3(1) (2022) | Journal | PDF


Correlative all-optical quantification of mass density and mechanics of subcellular compartments with fluorescence specificity

Raimund Schlüßler, Kyoohyun Kim, Martin Nötzel, Anna Taubenberger, Shada Abuhattum, Timon Beck, Paul Müller, Shovamaye Maharana, Gheorghe Cojoc, et al.

eLife (11) e68490 (2022) | Journal | PDF



2021

Real-Time Deformability Cytometry Detects Leukocyte Stiffening After Gadolinium-Based Contrast Agent Exposure

Angela Jacobi, Angela Ariza de Schellenberger, Yavuz Oguz Uca, Maik Herbig, Jochen Guck, Ingolf Sack

Investigative Radiology 56(12) 837-844 (2021) | Journal


Passive coupling of membrane tension and cell volume during active response of cells to osmosis

Chloé Roffay, Guillaume Molinard, Kyoohyun Kim, Marta Urbanska, Virginia Andrade, Victoria Barbarasa, Paulina Nowak, Vincent Mercier, José García-Calvo, et al.

Proceedings of the National Academy of Sciences of the United States of America 118(47) e2103228118 (2021) | Journal | PDF


Mapping Tumor Spheroid Mechanics in Dependence of 3D Microenvironment Stiffness and Degradability by Brillouin Microscopy

Vaibhav Mahajan, Timon Beck, Paulina Gregorczyk, André Ruland, Simon Alberti, Jochen Guck, Carsten Werner, Raimund Schlüßler, Anna V. Taubenberger

Cancers / Molecular Diversity Preservation International (MDPI) 13(21) 5549 (2021) | Journal | PDF


Matrix stiffness mechanosensing modulates the expression and distribution of transcription factors in Schwann cells

Gonzalo Rosso, Daniel Wehner, Christine Schweitzer, Stephanie Möllmert, Elisabeth Sock, Jochen Guck, Victor Shahin

Bioengineering & Translational Medicine e10257 (2021) | Journal | PDF


Physical phenotype of blood cells is altered in COVID-19

Markéta Kubánková, Bettina Hohberger, Jakob Hoffmanns, Julia Fürst, Martin Herrmann, Jochen Guck, Martin Kräter

Biophysical Journal 120(14) 2838-2847 (2021) | Journal | PDF


HIF2α is a Direct Regulator of Neutrophil Motility

Sundary Sormendi, Mathieu Deygas, Anupam Sinha, Anja Krüger, Ioannis Kourtzelis, Gregoire Le Lay, Mathilde Bernard, Pablo J. Sáez, Michael Gerlach, et al.

Blood 137(24) 3416-3427 (2021) | Journal | PDF


A unique macrophage subpopulation signals directly to progenitor cells to promote regenerative neurogenesis in the zebrafish spinal cord

Leonardo Cavone, Tess McCann, Louisa K. Drake, Erika A. Aguzzi, Ana-Maria Oprisoreanu, Elisa Pedersen, Soe Sandi, Jathurshan Selvarajah, Themistoklis M. Tsarouchas, et al.

Developmental Cell 56(11) 1617-+ (2021) | Journal


Know How to Regrow-Axon Regeneration in the Zebrafish Spinal Cord

Vasiliki Tsata, Daniel Wehner

Cells 10(6) 1404 (2021) | Journal | PDF


Efficient and gentle delivery of molecules into cells with different elasticity via Progressive Mechanoporation

Alena Uvizl, Ruchi Goswami, Shanil Durgeshkumar Gandhi, Martina Augsburg, Frank Buchholz, Jochen Guck, Jörg Mansfeld, Salvatore Girardo

Lab on a Chip 21 2437-2452 (2021) | Journal | PDF


Rapid computational cell-rotation around arbitrary axes in 3D with multi-core fiber

Jiawei Sun, Nektarios Koukourakis, Jochen Guck, Jürgen W. Czarske

Biomedical Optics Express 12(6) 3423-3437 (2021) | Journal | PDF


Toward deep biophysical cytometry: prospects and challenges

Kelvin C.M. Lee, Jochen Guck, Keisuke Goda, Kevin K. Tsia

Trends in Biotechnology 39(12) 1249-1262 (2021) | Journal


The Xenopus spindle is as dense as the surrounding cytoplasm

Abin Biswas, Kyoohyun Kim, Gheorghe Cojoc, Jochen Guck, Simone Reber

Developmental Cell 56(7) 967-975 (2021) | Journal


Compliant Substrates Enhance Macrophage Cytokine Release and NLRP3 Inflammasome Formation During Their Pro-Inflammatory Response

Joan-Carles Escolano, Anna V. Taubenberger, Shada Abuhattum, Christine Schweitzer, Aleeza Farrukh, Aránzazu del Campo, Clare E. Bryant, Jochen Guck

Frontiers in Cell and Developmental Biology 9 639815 (2021) | Journal | PDF


AIDeveloper: deep learning image classification in life science and beyond

Martin Kräter, Shada Abuhattum Hofemeier, Despina Soteriou, Angela Jacobi, Thomas Krüger, Jochen Guck, Maik Herbig

Advanced Science 2003743 (2021) | Journal | PDF


Mechanical properties of cell- and microgel bead-laden oxidized alginate-gelatin hydrogels

Thomas Distler, Lena Kretzschmar, Dominik Schneidereit, Salvatore Girardo, Ruchi Goswami, Oliver Friedrich, Rainer Detsch, Jochen Guck, Aldo R. Boccaccini, et al.

Biomaterials Science (9) 3051-3068 (2021) | Journal | PDF


A switch in pdgfrb+ cell-derived ECM composition prevents inhibitory scarring and promotes axon regeneration in the zebrafish spinal cord

Vasiliki Tsata, Stephanie Möllmert, Christine Schweitzer, Julia Kolb, Conrad Möckel, Benjamin Böhm, Gonzalo Rosso, Christian Lange, Mathias Lesche, et al.

Developmental Cell 56(4) 509-524 (2021) | Journal



2020

Reactive oligodendrocyte progenitor cells (re-)myelinate the regenerating zebrafish spinal cord

Vasiliki Tsata, Volker Kroehne, Daniel Wehner, Fabian Rost, Christian Lange, Cornelia Hoppe, Thomas Kurth, Susanne Reinhardt, Andreas Petzold, et al.

Development 147(24) dev193946 (2020) | Journal


Maturation of Monocyte-Derived DCs Leads to Increased Cellular Stiffness, Higher Membrane Fluidity, and Changed Lipid Composition

Jennifer J. Lühr, Nils Alex, Lukas Amon, Martin Kräter, Markéta Kubánková, Erdinc Sezgin, Christian H. K. Lehmann, Lukas Heger, Gordon F. Heidkamp, et al.

Frontiers in Immunology 11 590121 (2020) | Journal | PDF


Mechanical Adaptability of Tumor Cells in Metastasis

Valentin Gensbittel, Martin Kräter, Sébastien Harlepp, Ignacio Busnelli, Jochen Guck, Jacky G. Goetz

Developmental Cell (2020) | Journal


Optical quantification of intracellular mass density and cell mechanics in 3D mechanical confinement

Sadra Bakhshandeh, Hubert Taïeb, Raimund Schlüßler, Kyoohyun Kim, Timon Beck, Anna Taubenberger, Jochen Guck, Amaia Cipitria

Soft Matter (2020) | Journal | PDF


Estrogens Determine Adherens Junction Organization and E-Cadherin Clustering in Breast Cancer Cells via Amphiregulin

Philip Bischoff, Marja Kornhuber, Sebastian Dunst, Jakob Zell, Beatrix Fauler, Thorsten Mielke, Anna V. Taubenberger, Jochen Guck, Michael Oelgeschlaeger, et al.

iScience 23(11) 101683 (2020) | Journal | PDF


The Relative Densities of Cytoplasm and Nuclear Compartments Are Robust against Strong Perturbation

Kyoohyun Kim, Jochen Guck

Biophysical Journal 119(10) 1946-1957 (2020) | Journal | PDF


Acquired demyelination but not genetic developmental defects in myelination leads to brain tissue stiffness changes

Dominic Eberle, Georgia Fodelianaki, Thomas Kurth, Anna Jagielska, Stephanie Möllmert, Elke Ulbricht, Katrin Wagner, Anna V. Taubenberger, Nicolas Träber, et al.

Brain Multiphysics 1 100019 (2020) | Journal | PDF


Affinity Purification of Label-free Tubulins from Xenopus Egg Extracts

Sebastian Reusch, Abin Biswas, William Graham Hirst, Simone Reber

STAR Protocols 1(3) (2020) | Journal | PDF


Combined fluorescence, optical diffraction tomography and Brillouin microscopy

Raimund Schlüßler, Kyoohyun Kim, Martin Nötzel, Anna Taubenberger, Shada Abuhattum Hofemeier, Timon Beck, Paul Müller, Shovamayee Maharana, Gheorghe Cojoc, et al.

bioRxiv (2020) | PDF


Quantitative phase microscopy enables precise and efficient determination of biomolecular condensate composition

Patrick M. McCall, Kyoohyun Kim, Anatol W. Fritsch, J.M. Iglesias-Artola, L.M. Jawerth, Jie Wang, M. Ruer, J. Peychl, Andrey Poznyakovskiy, et al.

bioRxiv (2020) | PDF


Proteomic, biomechanical and functional analyses define neutrophil heterogeneity in systemic lupus erythematosus

Kathleen R. Bashant, Angel M. Aponte, Davide Randazzo, Paniz Rezvan Sangsari, Alexander J. T. Wood, Jack A. Bibby, Erin E. West, Arlette Vassallo, Zerai G. Manna, et al.

Annals of the Rheumatic Diseases 80(2) 209-218 (2020) | Journal


Buckling of an Epithelium Growing under Spherical Confinement

Anastasiya Trushko, Ilaria Di Meglio, Aziza Merzouki, Carles Blanch-Mercader, Shada Abuhattum, Jochen Guck, Kevin Alessandri, Pierre Nassoy, Karsten Kruse, et al.

Developmental Cell 54(5) 655-668 (2020) | Journal | PDF


Stretching and heating cells with light-nonlinear photothermal cell rheology

Constantin Huster, Devavrat Rekhade, Adina Hausch, Saeed Ahmed, Nicolas Hauck, Julian Thiele, Jochen Guck, Klaus Kroy, Gheorghe Cojoc

New Journal of Physics 22(8) 085003 (2020) | Journal | PDF


DryMass: handling and analyzing quantitative phase microscopy images of spherical, cell-sized objects

Paul Müller, Gheorghe Cojoc, Jochen Guck

BMC Bioinformatics (21) 221 1-8 (2020) | Journal


A comparison of microfluidic methods for high-throughput cell deformability measurements

Marta Urbanska, Hector E. Munoz, Josephine Shaw Bagnall, Oliver Otto, Scott R. Manalis, Dino Di Carlo, Jochen Guck

Nature Methods 17(6) 587-593 (2020) | Journal | PDF


Intelligent image-based deformation-assisted cell sorting with molecular specificity

Ahmad Ahsan Nawaz, Marta Urbanska, Maik Herbig, Martin Nötzel, Martin Kräter, Philipp Rosendahl, Christoph Herold, Nicole Töpfner, Markéta Kubánková, et al.

Nature Methods 17(6) 595-599 (2020) | Journal | PDF


Recent progress and current opinions in Brillouin Microscopy for life science application

Giuseppe Antonacci, Timon Beck, Alberto Bilenca, Jürgen Czarske, Kareem Elsayad, Jochen Guck, Kyoohyun Kim, Benedikt Krug, Francesca Palombo, et al.

Biophysical Reviews 12(3) 615-624 (2020) | Journal | PDF


RNA-Induced Conformational Switching and Clustering of G3BP Drive Stress Granule Assembly by Condensation

Jordina Guillén Boixet , Andrii Kopach , Alex S. Holehouse, Sina Wittmann , Marcus Jahnel, Raimund Schlüssler, Kyoohyun Kim, Irmela Trussina , Jie Wang , et al.

Cell 181(2) 346-361 (2020) | Journal


The mechanics of myeloid cells

Kathleen R. Bashant, Nicole Toepfner, Christopher J. Day, Nehal N. Mehta, Mariana J. Kaplan, Charlotte Summers, Jochen Guck, Edwin R. Chilvers

Biology of the Cell 112(4) 103-112 (2020) | Journal


Oncogenic signaling alters cell shape and mechanics to facilitate cell division under confinement

Helen K Matthews, Sushila Ganguli, Katarzyna Plak, Anna V. Taubenberger, Zaw Win, Max Williamson, Matthieu Piel, Jochen Guck, Buzz Baum

Developmental Cell 52(5) 563-573 (2020) | Journal


Zebrafish spinal cord repair is accompanied by transient tissue stiffening

Stephanie Möllmert, Maria A. Kharlamova, Tobias Hoche, Anna V. Taubenberger, Shada Abuhattum, Veronika Kuscha, Thomas Kurth, Michael Brand, Jochen Guck

Biophysical Journal 118(2) 448-463 (2020) | Journal



2019

Polyacrylamide Bead Sensors for in vivo Quantification of Cell-Scale Stress in Zebrafish Development

Nicole Träber, Klemens Uhlmann, Salvatore Girardo, Gokul Kesavan, Katrin Wagner, Jens Friedrichs, Ruchi Goswami, K Bai, Michael Brand, et al.

Scientific Reports 9(1) 17031 1-14 (2019) | Journal


Colloidal crystals of compliant microgel beads to study cell migration and mechanosensitivity in 3D

Katrin Wagner, Salvatore Girardo, Ruchi Goswami, Gonzalo Rosso, Elke Ulbricht, Paul Müller, Despina Soteriou, Nicole Träber, Jochen Guck

Soft Matter 15(47) 9776-9787 (2019) | Journal | PDF


CASP1 variants influence subcellular caspase-1 localization, pyroptosome formation, pro-inflammatory cell death and macrophage deformability

Franz Kapplusch, Felix Schulze, Sabrina Rabe-Matschewsky, Susanne Russ, Maik Herbig, Michael Christian Heymann, Katharina Schoepf , Robert Stein, Ursula Range, et al.

Clinical Immunology 208 108232 (2019) | Journal


Interaction of Axonal Chondrolectin with Collagen XIXa1 Is Necessary for Precise Neuromuscular Junction Formation

Ana-Maria Oprisoreanu, Hannah L. Smith, Sukrat Arya, Richard Webster, Zhen Zhong, Daniel Wehner, Marcos J. Cardozo, Thomas Becker, Kevin Talbot, et al.

Cell Reports 29(5) 1082-+ (2019) | Journal


Cell Mechanics Based Computational Classification of Red Blood Cells Via Unsupervised Machine Intelligence Applied to Morpho-Rheological Markers

Yan Ge, Philipp Rosenddahl, Claudio Duran, Sara Ciucci, Nicole Töpfner, Jochen Guck, Carlo Vittorio Cannistraci

IEEE/ACM Transactions on Computational Biology and Bioinformatics (2019) | Journal


Mechanical changes of peripheral nerve tissue microenvironment and their structural basis during development

Gonzalo Rosso, Jochen Guck

APL Bioengineering 3(3) 036107 (2019) | Journal


Some thoughts on the future of cell mechanics

Jochen Guck

Biophysical Review 11(15) 667-670 (2019) | Journal


Targeting Mechanoresponsive Proteins in Pancreatic Cancer: 4-Hydroxyacetophenone Blocks Dissemination and Invasion by Activating MYH14

Alexandra Surcel, Eric S. Schiffhauer, Dustin G. Thomas, Qingfeng Zhu, Kathleen T. DiNapoli, Maik Herbig, Oliver Otto, Hoku West-Foyle, Angela Jacobi, et al.

Cancer Research 79(18) 4665-4678 (2019) | Journal | PDF


nanite: using machine learning to assess the quality of atomic force microscopy-enabled nano-indentation data

Paul Müller, Shada Abuhattum Hofemeier, Stephanie Möllmert, Elke Ulbricht, Anna V. Taubenberger, Jochen Guck

BMC Bioinformatics (20) 465 (2019) | Journal | PDF


3D Microenvironment Stiffness Regulates Tumor Spheroid Growth and Mechanics via p21 and ROCK

Anna V. Taubenberger, Salvatore Girardo, Nicole Träber, Elisabeth Fischer-Friedrich, Martin Kräter, Katrin Wagner, Thomas Kurth, Isabel Richter, Barbara Haller, et al.

Advanced Biosystems 3(9) 1900128 (2019) | Journal


Effects of rigosertib on the osteo-hematopoietic niche in myelodysplastic syndromes

Ekaterina Balaian, Heike Weidner, Manja Wobus, Ulrike Baschant, Angela Jacobi, Anna Mies, Martin Bornhäuser, Jochen Guck, Lorenz C Hofbauer, et al.

Annals of Hematology 98(9) 2063-2072 (2019) | Journal


Controlling distinct signaling states in cultured cancer cells provides a new platform for drug discovery

Steven W. Poser, Oliver Otto, Carina Arps-Forker, Yan Ge, Maik Herbig, Cordula Andree, Konrad Gruetzmann, Melissa F. Adasme, Szymon Stodolak, et al.

FASEB JOURNAL 33(8) 9235-9249 (2019) | Journal


High-Throughput Microfluidic Characterization of Erythrocyte Shapes and Mechanical Variability

Felix Reichel, Johannes Mauer, Ahmad Ahsan Nawaz, Gerhard Gompper, Jochen Guck, Dmitry A. Fedosov

Biophysical Journal 117(1) 14-24 (2019) | Journal


Analysis of biomechanical properties of hematopoietic stem and progenitor cells with Real-Time Deformability Cytometry

Angela Jacobi, Philipp Rosendahl, Martin Kräter, Marta Urbanska, Maik Herbig, Jochen Guck

Methods in Molecular Biology 2017 135-148 (2019) | Book Chapter


Real-time deformability cytometry reveals sequential contraction and expansion during neutrophil priming

Kathleen R. Bashant, Arlette Vassallo, Christoph Herold, Reinhard Berner, Leonhard Menschner, Julien Subburayalu, Mariana J. Kaplan, Charlotte Summers, Jochen Guck, et al.

JOURNAL OF LEUKOCYTE BIOLOGY 105(6 SI) 1143-1153 (2019) | Journal


Morpho-Rheological Fingerprinting of Rod Photoreceptors Using Real-Time Deformability Cytometry

Tiago Santos-Ferreira, Maik Herbig, Oliver Otto, Madalena Carido, Mike O. Karl, Stylianos Michalakis, Jochen Guck, Marius Ader

Cytometry A 95(11) 1145-1157 (2019) | Journal | PDF


Spheroid Culture of Mesenchymal Stromal Cells Results in Morphorheological Properties Appropriate for Improved Microcirculation

Stefanie Tietze, Martin Kräter, Angela Jacobi, Anna Taubenberger, Maik Herbig, Rebekka Wehner, Marc Schmitz, Oliver Otto, Catrin List, et al.

Advanced Science 6(8) 1802104 (2019) | Journal | PDF


The relationship between metastatic potential and in vitro mechanical properties of osteosarcoma cells

Claude N. Holenstein, Aron Horvath, Barbara Schar, Angelina D. Schoenenberger, Maja Bollhalder, Nils Goedecke, Guido Bartalena, Oliver Otto, Maik Herbig, et al.

MOLECULAR BIOLOGY OF THE CELL 30(7 SI) 887-898 (2019) | Journal



2018

Accurate evaluation of size and refractive index for spherical objects in quantitative phase imaging

Paul Mueller, Mirjam Schuermann, Salvatore Girardo, Gheorghe Cojoc, Jochen Guck

OPTICS EXPRESS 26(8) 10729-10743 (2018) | Journal


Alterations in Cell Mechanics by Actin Cytoskeletal Changes Correlate with Strain-Specific Rubella Virus Phenotypes for Cell Migration and Induction of Apoptosis

Martin Kraeter, Jiranuwat Sapudom, Nicole Christin Bilz, Tilo Pompe, Jochen Guck, Claudia Claus

CELLS 7(9) 136 (2018) | Journal


Axonal Transport, Phase-Separated Compartments, and Neuron Mechanics - A New Approach to Investigate Neurodegenerative Diseases

Martin Noetzel, Gonzalo Rosso, Stephanie Moellmert, Anne Seifert, Raimund Schluessler, Kyoohyun Kim, Andreas Hermann, Jochen Guck

FRONTIERS IN CELLULAR NEUROSCIENCE 12 358 (2018) | Journal


Comparative study of cell mechanics methods

Pei-Hsun Wu, Dikla Raz-Ben Aroush, Atef Asnacios, Wei-Chiang Chen, Maxim Dokukin, Bryant L Doss, Pauline Durand, Andrew Ekpenyong, Jochen Guck, et al.

Nature methods 15(7) 491-498 (2018) | Journal


Detection of human disease conditions by single-cell morpho-rheological phenotyping of blood

Nicole Toepfner, Christoph Herold, Oliver Otto, Philipp Rosendahl, Angela Jacobi, Martin Kraeter, Julia Staechele, Leonhard Menschner, Maik Herbig, et al.

eLife 7 e29213 (2018) | Journal


Droplet-Assisted Microfluidic Fabrication and Characterization of Multifunctional Polysaccharide Microgels Formed by Multicomponent Reactions

Nicolas Hauck, Nalin Seixas, Silvia P. Centeno, Raimund Schluelsser, Gheorghe Cojoc, Paul Mueller, Jochen Guck, Dominik Woell, Ludger A. Wessjohann, et al.

POLYMERS 10(10) 1055 (2018) | Journal


High-throughput single-cell mechanical phenotyping with real-time deformability cytometry

Marta Urbanska, Philipp Rosendahl, Martin Kraeter, Jochen Guck

Methods in Cell Biology (2018) | Book Chapter


Intracellular Mass Density Increase Is Accompanying but Not Sufficient for Stiffening and Growth Arrest of Yeast Cells

Shada Abuhattum, Kyoohyun Kim, Titus M. Franzmann, Anne Esslinger, Daniel Midtvedt, Raimund Schluessler, Stephanie Mollmert, Hui-Shun Kuan, Simon Alberti, et al.

Frontiers in Physics 6 131 (2018) | Journal


Mechanical Mapping of Spinal Cord Growth and Repair in Living Zebrafish Larvae by Brillouin Imaging

Raimund Schluessler, Stephanie Moellmert, Shada Abuhattum, Gheorghe Cojoc, Paul Mueller, Kyoohyun Kim, Conrad Moeckel, Conrad Zimmermann, Jurgen Czarske, et al.

BIOPHYSICAL JOURNAL 115(5) 911-923 (2018) | Journal


Metabolic Profiling of Human Eosinophils

Linsey Porter, Nicole Toepfner, Kathleen R. Bashant, Jochen Guck, Margaret Ashcroft, Neda Farahi, Edwin R. Chilvers

FRONTIERS IN IMMUNOLOGY 9 1404 (2018) | Journal


Real-Time Deformability Cytometry: Label-Free Functional Characterization of Cells

Maik Herbig, Martin Kraeter, Katarzyna Plak, Paul Mueller, Jochen Guck, Oliver Otto

Methods in Molecular Biology (2018) | Book Chapter


Real-time fluorescence and deformability cytometry

Philipp Rosendahl, Katarzyna Plak, Angela Jacobi, Martin Kraeter, Nicole Toepfner, Oliver Otto, Christoph Herold, Maria Winzi, Maik Herbig, et al.

NATURE METHODS 15(5) 355-+ (2018) | Journal


Standardized microgel beads as elastic cell mechanical probes

S. Girardo, N. Traeber, K. Wagner, G. Cojoc, C. Herold, R. Goswami, R. Schluessler, S. Abuhattum, A. Taubenberger, et al.

JOURNAL OF MATERIALS CHEMISTRY B 6(39) 6245-6261 (2018) | Journal


Toll-Like Receptor-Mediated Upregulation of CXCL16 in Psoriasis Orchestrates Neutrophil Activation

Sabine Steffen, Susanne Abraham, Maik Herbig, Franziska Schmidt, Kristin Blau, Susann Meisterfeld, Stefan Beissert, Jochen Guck, Claudia Guenther

JOURNAL OF INVESTIGATIVE DERMATOLOGY 138(2) 344-354 (2018) | Journal



2017

Actin stress fiber organization promotes cell stiffening and proliferation of pre-invasive breast cancer cells

Sandra Tavares, Andre Filipe Vieira, Anna Verena Taubenberger, Margarida Araujo, Nuno Pimpao Martins, Catarina Bras-Pereira, Antonio Polonia, Maik Herbig, Clara Barreto, et al.

NATURE COMMUNICATIONS 8 15237 (2017) | Journal


Bone marrow niche-mimetics modulate HSPC function via integrin signaling

Martin Kraeter, Angela Jacobi, Oliver Otto, Stefanie Tietze, Katrin Mueller, David M. Poitz, Sandra Palm, Valentina M. Zinna, Ulrike Biehain, et al.

SCIENTIFIC REPORTS 7 2549 (2017) | Journal


Comparative study of cell mechanics methods

Pei-Hsun Wu, Dikla Raz-Ben Aroush, Atef Asnacios, Wei-Chiang Chen, Maxim Dokukin, Bryant L Doss, Pauline Durand, Andrew Ekpenyong, Jochen Guck, et al.

Nature methods 15(7) 491-498 (2018) | Journal


Enlightening discriminative network functional modules behind Principal Component Analysis separation in differential-omic science studies

Sara Ciucci, Yan Ge, Claudio Duran, Alessandra Palladini, Victor Jimenez-Jimenez, Luisa Maria Martinez-Sanchez, Yuting Wang, Susanne Sales, Andrej Shevchenko, et al.

SCIENTIFIC REPORTS 7 43946 (2017) | Journal


High-throughput cell mechanical phenotyping for label-free titration assays of cytoskeletal modifications

Stefan Golfier, Philipp Rosendahl, Alexander Mietke, Maik Herbig, Jochen Guck, Oliver Otto

CYTOSKELETON 74(8) 283-296 (2017) | Journal


Initiation of acute graft-versus-host disease by angiogenesis

Katarina Riesner, Yu Shi, Angela Jacobi, Martin Kraeter, Martina Kalupa, Aleixandria McGearey, Sarah Mertlitz, Steffen Cordes, Jens-Florian Schrezenmeier, et al.

BLOOD 129(14) 2021-2032 (2017) | Journal


Mechanical deformation induces depolarization of neutrophils

Andrew E. Ekpenyong, Nicole Toepfner, Christine Fiddler, Maik Herbig, Wenhong Li, Gheorghe Cojoc, Charlotte Summers, Jochen Guck, Edwin R. Chilvers

SCIENCE ADVANCES 3(6) e1602536 (2017) | Journal


Mechanical mismatch between Ras transformed and untransformed epithelial cells

Corinne Gullekson, Gheorghe Cojoc, Mirjam Schuermann, Jochen Guck, Andrew Pelling

SOFT MATTER 13(45) 8483-8491 (2017) | Journal


Mechanical Strain Promotes Oligodendrocyte Differentiation by Global Changes of Gene Expression

Anna Jagielska, Alexis L. Lowe, Ekta Makhija, Liliana Wroblewska, Jochen Guck, Robin J. M. Franklin, G. V. Shivashankar, Krystyn J. Van Vliet

FRONTIERS IN CELLULAR NEUROSCIENCE 11 93 (2017) | Journal


Niche WNT5A regulates the actin cytoskeleton during regeneration of hematopoietic stem cells

Christina Schreck, Rouzanna Istvanffy, Christoph Ziegenhain, Theresa Sippenauer, Franziska Ruf, Lynette Henkel, Florian Gaertner, Beate Vieth, M. Carolina Florian, et al.

JOURNAL OF EXPERIMENTAL MEDICINE 214(1) 165-181 (2017) | Journal


Numerical Simulation of Real-Time Deformability Cytometry To Extract Cell Mechanical Properties

M. Mokbel, D. Mokbel, A. Mietke, N. Traeber, S. Girardo, O. Otto, Jochen Guck, S. Aland

ACS BIOMATERIALS SCIENCE & ENGINEERING 3(11 SI) 2962-2973 (2017) | Journal


Plasmodium falciparum erythrocyte-binding antigen 175 triggers a biophysical change in the red blood cell that facilitates invasion

Marion Koch, Katherine E. Wright, Oliver Otto, Maik Herbig, Nichole D. Salinas, Niraj H. Tolia, Timothy J. Satchwell, Jochen Guck, Nicholas J. Brooks, et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 114(16) 4225-4230 (2017) | Journal


Roadmap for optofluidics

Paolo Minzioni, Roberto Osellame, Cinzia Sada, S. Zhao, F. G. Omenetto, Kristinn B. Gylfason, Tommy Haraldsson, Yibo Zhang, Aydogan Ozcan, et al.

JOURNAL OF OPTICS 19(9) 093003 (2017) | Journal


Single-cell mechanical phenotype is an intrinsic marker of reprogramming and differentiation along the mouse neural lineage

Marta Urbanska, Maria Winzi, Katrin Neumann, Shada Abuhattum, Philipp Rosendahl, Paul Mueller, Anna Taubenberger, Konstantinos Anastassiadis, Jochen Guck

Development 144(23 SI) 4313-4321 (2017) | Journal


Three-dimensional correlative single-cell imaging utilizing fluorescence and refractive index tomography

Mirjam Schuermann, Gheorghe Cojoc, Salvatore Girardo, Elke Ulbricht, Jochen Guck, Paul Mueller

Journal of Biophotonics 11(3) UNSP e201700145 (2017) | Journal


V-ATPase inhibition increases cancer cell stiffness and blocks membrane related Ras signaling - a new option for HCC therapy

Karin Bartel, Maria Winzi, Melanie Ulrich, Andreas Koeberle, Dirk Menche, Oliver Werz, Rolf Mueller, Jochen Guck, Angelika M. Vollmar, et al.

ONCOTARGET 8(6) 9476-9487 (2017) | Journal


Volume Transitions of Isolated Cell Nuclei Induced by Rapid Temperature Increase

Chii J. Chan, Wenhong Li, Gheorghe Cojoc, Jochen Guck

BIOPHYSICAL JOURNAL 112(6) 1063-1076 (2017) | Journal



2016

3D extracellular matrix interactions modulate tumour cell growth, invasion and angiogenesis in engineered tumour microenvironments

Anna V. Taubenberger, Laura J. Bray, Barbara Haller, Artem Shaposhnykov, Marcus Binner, Uwe Freudenberg, Jochen Guck, Carsten Werner

ACTA BIOMATERIALIA 36 73-85 (2016) | Journal


A Nanoprinted Model of Interstitial Cancer Migration Reveals a Link between Cell Deformability and Proliferation

Magdalini Panagiotakopoulou, Martin Bergert, Anna Taubenberger, Jochen Guck, Dimos Poulikakos, Aldo Ferrari

ACS NANO 10(7) 6437-6448 (2016) | Journal


A pH-driven transition of the cytoplasm from a fluid- to a solid-like state promotes entry into dormancy

Matthias Christoph Munder, Daniel Midtvedt, Titus Franzmann, Elisabeth Nueske, Oliver Otto, Maik Herbig, Elke Ulbricht, Paul Mueller, Anna Taubenberger, et al.

eLife 5 e09347 (2016) | Journal


Brain tissue stiffness is a sensitive marker for acidosis

Kathrin Holtzmann, Helene O. B. Gautier, Andreas F. Christ, Jochen Guck, Ragnhildur Thora Karadottir, Kristian Franze

JOURNAL OF NEUROSCIENCE METHODS 271 50-54 (2016) | Journal


Cell nuclei have lower refractive index and mass density than cytoplasm

Mirjam Schuermann, Jana Scholze, Paul Mueller, Jochen Guck, Chii J. Chan

JOURNAL OF BIOPHOTONICS 9(10) 1068-1076 (2016) | Journal


Chemotherapy impedes in vitro microcirculation and promotes migration of leukemic cells with impact on metastasis

Sruti V. Prathivadhi-Bhayankaram, Jianhao Ning, Michael Mimlitz, Carolyn Taylor, Erin Gross, Michael Nichols, Jochen Guck, Andrew E. Ekpenyong

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 479(4) 841-846 (2016) | Journal


Materials and technologies for soft implantable neuroprostheses

Stephanie P. Lacour, Gregoire Courtine, Jochen Guck

NATURE REVIEWS MATERIALS 1(10) UNSP 16063 (2016) | Journal


Mechanical phenotyping of primary human skeletal stem cells in heterogeneous populations by real-time deformability cytometry

Miguel Xavier, Philipp Rosendahl, Maik Herbig, Martin Kraeter, Daniel Spencer, Martin Bornhaeuser, Richard O. C. Oreffo, Hywel Morgan, Jochen Guck, et al.

INTEGRATIVE BIOLOGY 8(5) 616-623 (2016) | Journal


Mechanosensing is critical for axon growth in the developing brain

David E. Koser, Amelia J. Thompson, Sarah K. Foster, Asha Dwivedy, Eva K. Pillai, Graham K. Sheridan, Hanno Svoboda, Matheus Viana, Luciano da F. Costa, et al.

NATURE NEUROSCIENCE 19(12) 1592-1598 (2016) | Journal


The F-actin modifier villin regulates insulin granule dynamics and exocytosis downstream of islet cell autoantigen 512

Hassan Mziaut, Bernard Mulligan, Peter Hoboth, Oliver Otto, Anna Ivanova, Maik Herbig, Desiree Schumann, Tobias Hildebrandt, Jaber Dehghany, et al.

MOLECULAR METABOLISM 5(8) 656-668 (2016) | Journal



2015

A monolithic glass chip for active single-cell sorting based on mechanical phenotyping

Christoph Faigle, Franziska Lautenschlaeger, Graeme Whyte, Philip Homewood, Estela Martin-Badosa, Jochen Guck

LAB ON A CHIP 15(5) 1267-1275 (2015) | Journal


Association of the EGF-TM7 receptor CD97 expression with FLT3-ITD in acute myeloid leukemia

Manja Wobus, Martin Bornhaeuser, Angela Jacobi, Martin Kraeter, Oliver Otto, Claudia Ortlepp, Jochen Guck, Gerhard Ehninger, Christian Thiede, et al.

ONCOTARGET 6(36) 38804-38815 (2015) | Journal


Deformation of phospholipid vesicles in an optical stretcher

Ulysse Delabre, Kasper Feld, Eleonore Crespo, Graeme Whyte, Cecile Sykes, Udo Seifert, Jochen Guck

SOFT MATTER 11(30) 6075-6088 (2015) | Journal


Extracting Cell Stiffness from Real-Time Deformability Cytometry: Theory and Experiment

Alexander Mietke, Oliver Otto, Salvatore Girardo, Philipp Rosendahl, Anna Taubenberger, Stefan Golfier, Elke Ulbricht, Sebastian Aland, Jochen Guck, et al.

BIOPHYSICAL JOURNAL 109(10) 2023-2036 (2015) | Journal


Mechanotransduction in neutrophil activation and deactivation

Andrew E. Ekpenyong, Nicole Toepfner, Edwin R. Chilvers, Jochen Guck

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH 1853(11 SI) 3105-3116 (2015) | Journal


Myosin II Activity Softens Cells in Suspension

Chii J. Chan, Andrew E. Ekpenyong, Stefan Golfier, Wenhong Li, Kevin J. Chalut, Oliver Otto, Jens Elgeti, Jochen Guck, Franziska Lautenschlaeger

BIOPHYSICAL JOURNAL 108(8) 1856-1869 (2015) | Journal


ODTbrain: a Python library for full-view, dense diffraction tomography

Paul Mueller, Mirjam Schuermann, Jochen Guck

BMC BIOINFORMATICS 16 367 (2015) | Journal


Real-time deformability cytometry: on-the-fly cell mechanical phenotyping

Oliver Otto, Philipp Rosendahl, Alexander Mietke, Stefan Golfier, Christoph Herold, Daniel Klaue, Salvatore Girardo, Stefano Pagliara, Andrew Ekpenyong, et al.

NATURE METHODS 12(3) 199-+ (2015) | Journal


Refractive index measurements of single, spherical cells using digital holographic microscopy

Mirjam Schuermann, Jana Scholze, Paul Mueller, Chii J. Chan, Andrew E. Ekpenyong, Kevin J. Chalut, Jochen Guck

Methods in Cell Biology (2015) | Book Chapter


SAMHD1 prevents autoimmunity by maintaining genome stability

Stefanie Kretschmer, Christine Wolf, Nadja Koenig, Wolfgang Staroske, Jochen Guck, Martin Haeusler, Hella Luksch, Laura A. Nguyen, Baek Kim, et al.

ANNALS OF THE RHEUMATIC DISEASES 74(3) e17 (2015) | Journal



2014

Actin polymerization as a key innate immune effector mechanism to control Salmonella infection

Si Ming Man, Andrew Ekpenyong, Panagiotis Tourlomousis, Sarra Achouri, Eugenia Cammarota, Katherine Hughes, Alessandro Rizzo, Gilbert Ng, John A. Wright, et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 111(49) 17588-17593 (2014) | Journal


Direct observation of light focusing by single photoreceptor cell nuclei

Zuzanna Blaszczak, Moritz Kreysing, Jochen Guck

OPTICS EXPRESS 22(9) 11043-11060 (2014) | Journal


Dynamic operation of optical fibres beyond the single-mode regime facilitates the orientation of biological cells

Moritz Kreysing, Dino Ott, Michael J. Schmidberger, Oliver Otto, Mirjam Schuermann, Estela Martin-Badosa, Graeme Whyte, Jochen Guck

NATURE COMMUNICATIONS 5 5481 (2014) | Journal


Grouped retinae and tapetal cups in some Teleostian fish: Occurrence, structure, and function

Mike Francke, Moritz Kreysing, Andreas Mack, Jacob Engelmann, Anett Karl, Felix Makarov, Jochen Guck, Mathias Kolle, Hartwig Wolburg, et al.

PROGRESS IN RETINAL AND EYE RESEARCH 38 43-69 (2014) | Journal


Impact of heating on passive and active biomechanics of suspended cells

C. J. Chan, G. Whyte, L. Boyde, G. Salbreux, Jochen Guck

INTERFACE FOCUS 4(2 SI) 20130069 (2014) | Journal


Separation of blood cells with differing deformability using deterministic lateral displacement

David Holmes, Graeme Whyte, Joe Bailey, Nuria Vergara-Irigaray, Andrew Ekpenyong, Jochen Guck, Tom Duke

INTERFACE FOCUS 4(6) UNSP 20140011 (2014) | Journal


The relationship between glial cell mechanosensitivity and foreign body reactions in the central nervous system

Pouria Moshayedi, Gilbert Ng, Jessica C. F. Kwok, Giles S. H. Yeo, Clare E. Bryant, James W. Fawcett, Kristian Franze, Jochen Guck

BIOMATERIALS 35(13) 3919-3925 (2014) | Journal



2013

Bacterial infection of macrophages induces decrease in refractive index

Andrew E. Ekpenyong, Si Ming Man, Sarra Achouri, Clare E. Bryant, Jochen Guck, Kevin J. Chalut

JOURNAL OF BIOPHOTONICS 6(5) 393-397 (2013) | Journal


Elastic theory for the deformation of a solid or layered spheroid under axisymmetric loading

Lars Boyde, Andrew Ekpenyong, Graeme Whyte, Jochen Guck

ACTA MECHANICA 224(4) 819-839 (2013) | Journal


Mechanics in Neuronal Development and Repair

Kristian Franze, Paul A. Janmey, Jochen Guck

Annual Review of Biomedical Engineering 15(1) 227-251 (2013) | Journal


Mechanics Meets Medicine

Jochen Guck, Edwin R. Chilvers

SCIENCE TRANSLATIONAL MEDICINE 5(212) 212fs41 (2013) | Journal



2012

Changes in Ect2 Localization Couple Actomyosin-Dependent Cell Shape Changes to Mitotic Progression

Helen K. Matthews, Ulysse Delabre, Jennifer L. Rohn, Jochen Guck, Patricia Kunda, Buzz Baum

DEVELOPMENTAL CELL 23(2) 371-383 (2012) | Journal


Chromatin Decondensation and Nuclear Softening Accompany Nanog Downregulation in Embryonic Stem Cells

Kevin J. Chalut, Markus Hoepfler, Franziska Lautenschlaeger, Lars Boyde, Chii Jou Chan, Andrew Ekpenyong, Alfonso Martinez-Arias, Jochen Guck

BIOPHYSICAL JOURNAL 103(10) 2060-2070 (2012) | Journal


Comparison of stresses on homogeneous spheroids in the optical stretcher computed with geometrical optics and generalized Lorenz-Mie theory

Lars Boyde, Andrew Ekpenyong, Graeme Whyte, Jochen Guck

APPLIED OPTICS 51(33) 7934-7944 (2012) | Journal


Coupling of Active Motion and Advection Shapes Intracellular Cargo Transport

Philipp Khuc Trong, Jochen Guck, Raymond E. Goldstein

PHYSICAL REVIEW LETTERS 109(2) 028104 (2012) | Journal


Live Cells as Optical Fibers in the Vertebrate Retina

Andreas Reichenbach, Kristian Franze, Silke Agte, Stephan Junek, Antje Wurm, Jens Grosche, Alexej Savvinov, Jochen Guck, Serguei N. Skatchkov

SELECTED TOPICS ON OPTICAL FIBER TECHNOLOGY 247-270 (2012)


Mechanical Environment Modulates Biological Properties of Oligodendrocyte Progenitor Cells

Anna Jagielska, Adele L. Norman, Graeme Whyte, Krystyn J. Van Vliet, Jochen Guck, Robin J. M. Franklin

STEM CELLS AND DEVELOPMENT 21(16) 2905-2914 (2012) | Journal


Photonic Crystal Light Collectors in Fish Retina Improve Vision in Turbid Water

Moritz Kreysing, Roland Pusch, Dorothee Haverkate, Meik Landsberger, Jacob Engelmann, Janina Ruiter, Carlos Mora-Ferrer, Elke Ulbricht, Jens Grosche, et al.

SCIENCE 336(6089) 1700-1703 (2012) | Journal


Quantifying cellular differentiation by physical phenotype using digital holographic microscopy

Kevin J. Chalut, Andrew E. Ekpenyong, Warren L. Clegg, Isabel C. Melhuish, Jochen Guck

INTEGRATIVE BIOLOGY 4(3) 280-284 (2012) | Journal


Validation and perspectives of a femtosecond laser fabricated monolithic optical stretcher

Nicola Bellini, Francesca Bragheri, Ilaria Cristiani, Jochen Guck, Roberto Osellame, Graeme Whyte

BIOMEDICAL OPTICS EXPRESS 3(10) 2658-2668 (2012) | Journal


Viscoelastic Properties of Differentiating Blood Cells Are Fate- and Function-Dependent

Andrew E. Ekpenyong, Graeme Whyte, Kevin Chalut, Stefano Pagliara, Franziska Lautenschlaeger, Christine Fiddler, Stephan Paschke, Ulrich F. Keyser, Edwin R. Chilvers, et al.

PLOS ONE 7(9) e45237 (2012) | Journal



2011

3D inverted colloidal crystals in realistic cell migration assays for drug screening applications

Joakim da Silva, Franziska Lautenschlaeger, Cheng-Hwa R. Kuo, Jochen Guck, Easan Sivaniah

INTEGRATIVE BIOLOGY 3(12) 1202-1206 (2011) | Journal


Exact analytical expansion of an off-axis Gaussian laser beam using the translation theorems for the vector spherical harmonics

Lars Boyde, Kevin J. Chalut, Jochen Guck

APPLIED OPTICS 50(7) 1023-1033 (2011) | Journal


Near- and far-field scattering from arbitrary three-dimensional aggregates of coated spheres using parallel computing

Lars Boyde, Kevin J. Chalut, Jochen Guck

PHYSICAL REVIEW E 83(2) 026701 (2011) | Journal


Spatial mapping of the mechanical properties of the living retina using scanning force microscopy

Kristian Franze, Mike Francke, Katrin Guenter, Andreas F. Christ, Nicole Koerber, Andreas Reichenbach, Jochen Guck

SOFT MATTER 7(7) 3147-3154 (2011) | Journal



2010

Biophotonic techniques for the study of malaria-infected red blood cells

Jakob M. A. Mauritz, Alessandro Esposito, Teresa Tiffert, Jeremy N. Skepper, Alice Warley, Young-Zoon Yoon, Pietro Cicuta, Virgilio L. Lew, Jochen Guck, et al.

MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING 48(10 SI) 1055-1063 (2010) | Journal


Critical review: cellular mechanobiology and amoeboid migration

Jochen Guck, Franziska Lautenschlaeger, Stephan Paschke, Michael Beil

INTEGRATIVE BIOLOGY 2(11-12) 575-583 (2010) | Journal


Detection of Plasmodium falciparum-infected red blood cells by optical stretching

Jakob M. A. Mauritz, Teresa Tiffert, Rachel Seear, Franziska Lautenschlaeger, Alessandro Esposito, Virgilio L. Lew, Jochen Guck, Clemens F. Kaminski

JOURNAL OF BIOMEDICAL OPTICS 15(3) 030517 (2010) | Journal


Mechanical difference between white and gray matter in the rat cerebellum measured by scanning force microscopy

Andreas F. Christ, Kristian Franze, Helene Gautier, Pouria Moshayedi, James Fawcett, Robin J. M. Franklin, Ragnhildur T. Karadottir, Jochen Guck

JOURNAL OF BIOMECHANICS 43(15) 2986-2992 (2010) | Journal


Mechanosensitivity of astrocytes on optimized polyacrylamide gels analyzed by quantitative morphometry

Pouria Moshayedi, Luciano da F. Costa, Andreas Christ, Stephanie P. Lacour, James Fawcett, Jochen Guck, Kristian Franze

JOURNAL OF PHYSICS-CONDENSED MATTER 22(19) 194114 (2010) | Journal


Mesenchymal Stem Cell Mechanics from the Attached to the Suspended State

John M. Maloney, Dessy Nikova, Franziska Lautenschlaeger, Emer Clarke, Robert Langer, Jochen Guck, Krystyn J. Van Vliet

BIOPHYSICAL JOURNAL 99(8) 2479-2487 (2010) | Journal


Micro and nanotechnology for biological and biomedical applications

Chwee Teck Lim, Jongyoon Han, Jochen Guck, Horacio Espinosa

MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING 48(10) 941-943 (2010) | Journal


Monitoring of laser micromanipulated optically trapped cells by digital holographic microscopy

Bjoern Kemper, Patrik Langehanenberg, Alexander Hoeink, Gert von Bally, Falk Wottowah, Stefan Schinkinger, Jochen Guck, Josef Kaes, Ilona Bredebusch, et al.

JOURNAL OF BIOPHOTONICS 3(7) 425-431 (2010) | Journal


Physical insight into light scattering by photoreceptor cell nuclei

Moritz Kreysing, Lars Boyde, Jochen Guck, Kevin J. Chalut

OPTICS LETTERS 35(15) 2639-2641 (2010) | Journal


The biophysics of neuronal growth

Kristian Franze, Jochen Guck

REPORTS ON PROGRESS IN PHYSICS 73(9) 094601 (2010) | Journal


The cavity-to-cavity migration of leukaemic cells through 3D honey-combed hydrogels with adjustable internal dimension and stiffness

Joakim da Silva, Franziska Lautenschlaeger, Easan Sivaniah, Jochen Guck

BIOMATERIALS 31(8) 2201-2208 (2010) | Journal



2009

Do cells care about physics?

Jochen Guck

PHYSICS WORLD 22(7) 31-34 (2009)


Interaction of Gaussian beam with near-spherical particle: an analytic-numerical approach for assessing scattering and stresses

Lars Boyde, Kevin J. Chalut, Jochen Guck

JOURNAL OF THE OPTICAL SOCIETY OF AMERICA A-OPTICS IMAGE SCIENCE AND VISION 26(8) 1814-1826 (2009) | Journal


Nuclear Architecture of Rod Photoreceptor Cells Adapts to Vision in Mammalian Evolution

Irina Solovei, Moritz Kreysing, Christian Lanctot, Sueleyman Koesem, Leo Peichl, Thomas Cremer, Jochen Guck, Boris Joffe

CELL 137(2) 356-368 (2009) | Journal


Oral Cancer Diagnosis by Mechanical Phenotyping

Torsten W. Remmerbach, Falk Wottawah, Julia Dietrich, Bryan Lincoln, Christian Wittekind, Jochen Guck

CANCER RESEARCH 69(5) 1728-1732 (2009) | Journal



2008

Quantifying the contribution of actin networks to the elastic strength of fibroblasts

Revathi Ananthakrishnan, Jochen Guck, Falk Wottawah, Stefan Schinkinger, Bryan Lincoln, Maren Romeyke, Tess Moon, Josef Kaes

JOURNAL OF THEORETICAL BIOLOGY 255(1) 162-162 (2008) | Journal


The optical cell rotator

Moritz K. Kreysing, Tobias Kiessling, Anatol Fritsch, Christian Dietrich, Jochen Guck, Josef A. Kaes

OPTICS EXPRESS 16(21) 16984-16992 (2008) | Journal



2007

Fluorescence ratio thermometry in a microfluidic dual-beam laser trap

Susanne Ebert, Kort Travis, Bryan Lincoln, Jochen Guck

OPTICS EXPRESS 15(23) 15493-15499 (2007) | Journal


High-throughput rheological measurements with an optical stretcher

Bryan Lincoln, Falk Wottawah, Stefan Schinkinger, Susanne Ebert, Jochen Guck

Methods in Cell Biology 83 397-423 (2007) | Journal


Müller cells are living optical fibers in the vertebrate retina

Kristian Franze, Jens Grosche, Serguei N. Skatchkov, Stefan Schinkinger, Christian Foja, Detlev Schlid, Ortrud Uckermann, Kort Travis, Andreas Reichenbach, et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 104(20) 8287-8292 (2007) | Journal


Reconfigurable microfluidic integration of a dual-beam laser trap with biomedical applications

Bryan Lincoln, Stefan Schinkinger, Kort Travis, Falk Wottawah, Susanne Ebert, Frank Sauer, Jochen Guck

BIOMEDICAL MICRODEVICES 9(5) 703-710 (2007) | Journal



2006

The microscopy cell (MicCell), a versatile modular flowthrough system for cell biology, biomaterial research, and nanotechnology

FU Gast, PS Dittrich, P Schwille, M Weigel, M Mertig, J Opitz, U Queitsch, S Diez, B Lincoln, et al.

MICROFLUIDICS AND NANOFLUIDICS 2(1) 21-36 (2006) | Journal


Viscoelastic properties of individual glial cells and neurons in the CNS

Yun-Bi Lu, Kristian Franze, Gerald Seifert, Christian Steinhaeuser, Frank Kirchhoff, Hartwig Wolburg, Jochen Guck, Paul Janmey, Er-Qing Wei, et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 103(47) 17759-17764 (2006) | Journal



2005

Characterizing single suspended cells by optorheology

F Wottawah, S Schinkinger, B Lincoln, S Ebert, K Muller, F Sauer, K Travis, Jochen Guck

ACTA BIOMATERIALIA 1(3) 263-271 (2005) | Journal


Modelling the structural response of an eukaryotic cell in the optical stretcher

R Ananthakrishnan, Jochen Guck, F Wottawah, S Schinkinger, B Lincoln, M Romeyke, J Kas

CURRENT SCIENCE 88(9) 1434-1440 (2005)


Optical deformability as an inherent cell marker for testing malignant transformation and metastatic competence

Jochen Guck, S Schinkinger, B Lincoln, F Wottawah, S Ebert, M Romeyke, D Lenz, HM Erickson, R Ananthakrishnan, et al.

BIOPHYSICAL JOURNAL 88(5) 3689-3698 (2005) | Journal


Optical rheology of biological cells

F Wottawah, S Schinkinger, B Lincoln, R Ananthakrishnan, M Romeyke, Jochen Guck, J Kas

PHYSICAL REVIEW LETTERS 94(9) 098103 (2005) | Journal



2004

Deformability-based flow cytometry

B Lincoln, HM Erickson, S Schinkinger, F Wottawah, D Mitchell, S Ulvick, C Bilby, Jochen Guck

CYTOMETRY PART A 59A(2) 203-209 (2004) | Journal



2002

Stretching biological cells with light

Jochen Guck, R Ananthakrishnan, CC Cunningham, J Kas

JOURNAL OF PHYSICS-CONDENSED MATTER 14(19) PII S0953-8984(02)29158-4 4843-4856 (2002) | Journal



2001

The optical stretcher: A novel laser tool to micromanipulate cells

Jochen Guck, R Ananthakrishnan, H Mahmood, TJ Moon, CC Cunningham, J Kas

BIOPHYSICAL JOURNAL 81(2) 767-784 (2001) | Journal



2000

Optical deformability of soft biological dielectrics

Jochen Guck, R Ananthakrishnan, TJ Moon, CC Cunningham, J Kas

PHYSICAL REVIEW LETTERS 84(23) 5451-5454 (2000) | Journal


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