Taking Detection to the Limit: Biosensing with Microresonators

26.03.2014, 09:00

PD Frank Vollmer, MPL Erlangen

PD Frank Vollmer
Max Planck Institute for the Science of Light;
Laboratory of Nanophotonics & Biosensing
Taking Detection to the Limit: Biosensing with Microresonators

Biosensing relies on the physics of microdevices for detecting molecules and their interactions. Here it is highly desirable to develop label-free transducers operating at ultimate detection limits. We have now demonstrated such capability in the optical and mechanical domains using microresonators as highly sensitive, fast and versatile transducers.

I will show our results on engineering an optical microcavity biosensor capable of detecting single molecules and their interactions. We achieve unparalleled sensitivity and time resolution by enhancing the already extreme sensitivity of Whispering Gallery Modes with the principle of plasmon resonance. I will then show analogous measurements in the mechanical domain where we couple a microresonator to a quartz crystal microbalance. If time permits, I will also highlight some of our recent works on biosensing with DNA nanotechnology, enabling single nanoparticle detection with surface plasmon polaritons, real-time analysis of a biomarker secreted by nerve cells, and photonic crystal devices in stand off detection.

For more info please go to our website: www.mpl.mpg.de/research-groups/bfp/
Time and Place:
Wednesday, March 26th at 09:00
Large Seminar Room